18065-1-AP targets ALDOB in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested ApplicationsIHC, IP, WB, ELISA Application Description

Cited ApplicationsWB, IP, IF, IHC

Tested ReactivityHuman, Mouse, Rat

Cited ReactivityHuman, Mouse, Rat

ImmunogenALDOB fusion protein Ag12695 种属同源性预测

Host / IsotypeRabbit / IgG

ClassPolyclonal

TypeAntibody

Full Namealdolase B, fructose-bisphosphate

SynonymsALDB, ALDOB, Liver type aldolase

Calculated Molecular Weight316 aa, 35 kDa

Observed Molecular Weight35-40 kDa

GenBank Accession NumberBC029399

Gene SymbolALDOB

Gene ID (NCBI)229

RRIDAB_2273968

ConjugateUnconjugated

FormLiquid

Purification MethodAntigen affinity purification

UNIPROT IDP05062

Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Fructose-1,6-bisphosphate aldolase is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.Vertebrates have 3 aldolase isozymes, aldolase A (ALDOA), B (ALDOB), and C (ALDOC). Deficiency of this enzyme ALDOB causes an accumulation of fructose-1-phosphate after fructose intake, which results in toxic symptoms like vomiting, hypoglycemia, jaundice, elevated liver enzymes and hepatomegaly(PMID:22375183). This antibody may detect ALDOA.